Re: Antiangiogenic Activity of Prostate-Specific Antigen
نویسندگان
چکیده
منابع مشابه
Re: Antiangiogenic activity of prostate-specific antigen.
Although prostate-specific antigen (PSA) has been shown by Fortier et al. (1) to inhibit endothelial cell proliferation, migration, and invasion as well as metastatic spread, the value of these findings has to be questioned. This skepticism is due to the fact that, in all the experiments carried out, very high concentrations of PSA—equivalent to many thousands of ng/mL—were used. These high con...
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There are emerging data on novel tumor markers such as matrix metalloproteinase-2 (MMP-2 or gelatinase-A), which play a key role in tissue invasion and metastasis. We designed an investigation to assess the usefulness of MMP-2 activity as compared to prostate specific antigen (PSA) in cancer staging process. We have analyzed the circulating form of MMP-2 in serum samples of patients suffering f...
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Introduction: Prostatic adenocarcinoma is one the most common malignances and the second cause of death in males due to cancer. Prostate Specific Antigen (PZSA) serum level is the first marker to screen such patients. We aimed in this study, to assess the intensity of prostatic adenocarcinoma tissue staining with PSA staining method. Methods: In this corss-sectional study, prostatic adenocarcin...
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ژورنال
عنوان ژورنال: Journal of the National Cancer Institute
سال: 2000
ISSN: 1460-2105
DOI: 10.1093/jnci/92.4.345